Gout is a form of inflammatory arthritis caused by the deposition of monosodium urate crystals in joints and soft tissues, resulting from chronically elevated serum uric acid levels.

How is gout diagnosed?

The gold standard is joint fluid analysis identifying monosodium urate crystals under polarized microscopy.

What uric acid level is considered high?

A serum uric acid level above 6.8 mg/dL is above the saturation point. The ACR treatment target is below 6.0 mg/dL.

What is the fastest way to stop a gout flare?

The ACR recommends colchicine, NSAIDs, or corticosteroids as first-line options for acute gout flares.

What foods trigger gout flares?

High-purine foods like organ meats and certain seafood, alcohol especially beer, and fructose-sweetened beverages.

Gout cannot be cured but can be effectively controlled with urate-lowering therapy to stop flares and dissolve crystal deposits.

Gout Research - GoutSavvy.com

The Monthly Infusion That Could Transform Uncontrolled Gout: Inside the NASP DISSOLVE Data

August 17, 2026 by GoutSavvy Editorial Team

NASP, a monthly intravenous infusion combining nanoencapsulated sirolimus and pegadricase, produced complete tophus resolution in up to 70 percent of uncontrolled gout patients in phase 3 trials. Here is what the DISSOLVE data show.

Your Diabetes Drug Might Already Be Lowering Your Gout Risk

August 15, 2026 by GoutSavvy Editorial Team

SGLT2 inhibitors lower blood sugar and uric acid. New 2026 research shows they may also reduce gout flares and the need for allopurinol.

When Your Kidneys Fail, Your Gout Treatment Does Too: What’s Finally Changing

August 9, 2026August 9, 2026 by GoutSavvy Editorial Team

The Double Trap: Gout and Kidney Disease Your kidneys filter uric acid out of your blood. When they work well, they keep things balanced. When they don’t, uric acid builds up, crystals form in your joints, and a gout attack hits you like a freight train. That’s the basics of the gout-kidney connection, and it’s … Read more

The Real Reason Your Gout Flares Hit So Fast and Hurt So Much

August 7, 2026August 7, 2026 by GoutSavvy Editorial Team

Why do gout flares go from zero to unbearable in hours? The answer is NLRP3, a tiny alarm system inside your immune cells. Once you understand how it works, everything about gout pain makes sense.

Why Your Workout Might Be Triggering Your Gout: The Lactic Acid Problem Nobody Mentioned

August 6, 2026August 6, 2026 by GoutSavvy Editorial Team

Hard exercise produces lactic acid that competes with uric acid for kidney excretion. Here is what the research says about exercising safely with gout.

Why Your Uric Acid Won’t Drop Even After Cutting Protein: The Insulin Trap Nobody Warned You About

August 3, 2026August 2, 2026 by GoutSavvy Editorial Team

You Cut the Steak, Dropped the Eggs, and Your Uric Acid Still Won’t Move If you’ve been dealing with gout for a while, you’ve probably heard the same advice a hundred times: cut the purines. Drop the red meat. Skip the seafood. Lay off the beer. So you did. You swapped steak for salads. You … Read more