In-depth expert guides covering the most important gout topics with evidence-based recommendations.
The First Pill That May Dissolve Gout Tophi: What Pozdeutinurad Could Mean for You If you have gout tophi, those hard lumps of uric acid crystals under your skin, you already know the frustration. You take your allopurinol or febuxostat faithfully. Your blood tests show lower uric acid. But the lumps stay. They damage your … Read more
Picture this: you’re 55, healthy enough, and then one day your knee swells up for no obvious reason. The pain is excruciating. You go to the ER. The doctor mentions arthritis. Maybe pseudogout. Gout? That can’t be right, gout is a man’s disease, isn’t it? Actually, no. That’s a myth that’s been floating around for … Read more
You’ve heard the standard advice. Lose weight. Cut purines. Stop drinking. Most people stop there and wonder why they’re still flaring. The problem isn’t that this advice is wrong—it’s incomplete. Successful gout management requires understanding the mechanics, avoiding the common traps, and building systems that work when you’re busy, stressed, or just human. This guide … Read more
Here’s something that flew under the radar in the American gout community: In May 2026, China approved its first-ever IL-1β inhibitor specifically for acute gout flares. It’s called Fuxinqibai (development code: Efpelibikibart), marketed as Jinbeixin, and the clinical data is genuinely impressive. As someone who’s spent years tracking gout treatments for American patients, I find … Read more
For people diagnosed with gout, understanding your medication options is one of the most important steps in managing this condition. Two of the most commonly prescribed urate-lowering therapies (ULT) are allopurinol and febuxostat (commonly known by the brand name Uloric). Both medications work by reducing uric acid production in the body, but they have different … Read more
# Prednisone vs Colchicine for Gout Flares: When to Use Each One When nonsteroidal anti-inflammatory drugs (NSAIDs) aren’t an option for treating your gout flare, two alternatives stand out: colchicine and corticosteroids like prednisone. Both are American College of Rheumatology (ACR)-recommended treatments, but they work differently and suit different patient populations. Understanding when each medication … Read more